Dengue fever
About Dengue fever
- Dengue is a mosquito-borne viral infection.
- Dengue virus is transmitted by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, Ae. albopictus.
- These mosquitoes are also vectors of chikungunya, yellow fever and Zika viruses.
- Dengue is found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas.
- The virus responsible for causing dengue, is called dengue virus (DENV).
- There are four DENV serotypes, meaning that it is possible to be infected four times.
Signs and symptoms
- Dengue is a severe, flu-like illness that affects infants, young children and adults, but seldom causes death.
- Symptoms usually last for 2–7 days, after an incubation period of 4–10 days after the bite from an infected mosquito.
- The World Health Organization classifies dengue into 2 major categories: dengue (with / without warning signs) and severe dengue.
Treatment
- There is no specific treatment for dengue fever.
- Fever reducers and pain killers can be taken to control the symptoms of muscle aches and pains, and fever.
Vaccination against dengue
- The first dengue vaccine, Dengvaxia (CYD-TDV) was licensed in December 2015 and has now been approved by regulatory authorities in ~20 countries.
Why in News?
- Two independent research studies — one from a group in Israel and another from the Council of Scientific and Industrial Research-Indian Institute of Chemical Biology (CSIR-IICB) in Kolkata — show that tests specific to check for dengue sometimes led to a positive SARS-CoV-2 test.
- The scientists warn that this could lead to misdiagnosis and skew public health responses in places where dengue is endemic and known to seasonally spike.
More in the News
- The study by CSIR-IICB used dengue antibody- positive serum samples from 2017 (pre-dating the COVID-19 outbreak) and produced false-positive results in SARS-CoV-2 IgG/IgM rapid strip tests.
- Similarly the study by Israel had put some people who tested positive for SARS-CoV-2 test to dengue testing using antibodies.
- Around 22% samples returned positive for dengue virus.
Further research needed
- Because the viruses that cause dengue and coronaviruses belong to entirely different families, it is not expected for one to show affinity to the other.
- However, the above finding prompts deeper investigation into whether there are crucial similarities in the structure of these viruses.
- Better understanding of the relationship between the two viruses could help understand variations in mortality.
- India and Brazil are highly endemic for dengue as are many parts of southeast Asia.
Reference:
- https://www.thehindu.com/sci-tech/health/dengue-virus-tests-may-sometimes-return-positive-for-coronavirus-study/article32416613.ece
- https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
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